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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
6.67
Human Site:
S548
Identified Species:
12.22
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
S548
P
D
D
M
K
G
I
S
G
G
S
S
S
S
S
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
G515
S
I
P
W
Q
N
E
G
C
L
T
M
V
P
S
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
V314
H
L
H
Q
R
R
I
V
Y
R
D
L
K
P
E
Dog
Lupus familis
XP_542675
460
51324
E446
D
M
K
G
I
A
V
E
E
A
A
P
A
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
T548
P
D
D
M
K
G
I
T
T
E
E
A
A
P
T
Rat
Rattus norvegicus
Q63651
564
63750
T548
P
D
D
M
K
G
I
T
V
E
E
A
A
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
P548
P
D
D
M
R
D
G
P
G
E
D
E
T
A
S
Chicken
Gallus gallus
NP_990026
593
64642
A577
P
P
D
L
D
P
N
A
E
P
G
S
G
G
G
Frog
Xenopus laevis
NP_001087513
575
66421
G541
P
P
D
L
D
W
R
G
L
P
S
P
Q
P
K
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
A419
S
I
T
E
A
T
E
A
F
L
G
F
S
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
A669
T
P
D
L
Q
I
N
A
A
P
E
P
D
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
D572
V
M
W
N
L
R
P
D
G
I
N
M
D
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
Q794
D
I
N
D
G
F
N
Q
E
K
N
M
N
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
46.6
46.6
N.A.
40
20
20
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
20
13.3
26.6
N.A.
73.3
73.3
N.A.
60
33.3
26.6
20
N.A.
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
24
8
8
8
16
24
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
16
31
54
8
16
8
0
8
0
0
16
0
16
0
0
% D
% Glu:
0
0
0
8
0
0
16
8
24
24
24
8
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
24
8
16
24
8
16
0
8
8
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
24
0
0
8
8
31
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
24
0
0
0
0
8
0
0
8
8
16
% K
% Leu:
0
8
0
24
8
0
0
0
8
16
0
8
0
0
0
% L
% Met:
0
16
0
31
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
8
8
0
8
24
0
0
0
16
0
8
8
0
% N
% Pro:
47
24
8
0
0
8
8
8
0
24
0
24
0
39
0
% P
% Gln:
0
0
0
8
16
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
16
16
8
0
0
8
0
0
0
0
8
% R
% Ser:
16
0
0
0
0
0
0
8
0
0
16
16
16
16
31
% S
% Thr:
8
0
8
0
0
8
0
16
8
0
8
0
8
0
16
% T
% Val:
8
0
0
0
0
0
8
8
8
0
0
0
8
0
0
% V
% Trp:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _